Structure of PDB 1h8a Chain A

Receptor sequence
>1h8aA (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
VDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKK
VEQLSRELSTLRNLFKQL
3D structure
PDB1h8a Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
ChainA
Resolution2.23 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K269 Y274 R278 N281 N282 R286 R289 K3 Y8 R12 N15 N16 R20 R23 PDBbind-CN: Kd=25.4nM
BS02 dna A R280 K287 S288 K291 R14 K21 S22 K25 PDBbind-CN: Kd=25.4nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1h8a, PDBe:1h8a, PDBj:1h8a
PDBsum1h8a
PubMed11792321
UniProtP17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)

[Back to BioLiP]