Structure of PDB 1h88 Chain A

Receptor sequence
>1h88A (length=70) Species: 9606 (Homo sapiens) [Search protein sequence]
VDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKK
VEQLSRELSTLRNLFKQLPE
3D structure
PDB1h88 Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K269 Y274 R278 N281 N282 R286 R289 K3 Y8 R12 N15 N16 R20 R23 PDBbind-CN: Kd=35.3nM
BS02 dna A K287 S288 R289 K21 S22 R23 PDBbind-CN: Kd=35.3nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1h88, PDBe:1h88, PDBj:1h88
PDBsum1h88
PubMed11792321
UniProtP17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)

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