Structure of PDB 1h7u Chain A

Receptor sequence
>1h7uA (length=307) Species: 9606 (Homo sapiens) [Search protein sequence]
VVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENF
EGLTLKGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPR
PRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVS
CTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSV
CEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAK
VCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINQILLQEEKLLLAVLKT
SLIGMFD
3D structure
PDB1h7u Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A N45 A49 L83 E109 L111 T155 N15 A19 L53 E58 L60 T104
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0032300 mismatch repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h7u, PDBe:1h7u, PDBj:1h7u
PDBsum1h7u
PubMed11574484
UniProtP54278|PMS2_HUMAN Mismatch repair endonuclease PMS2 (Gene Name=PMS2)

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