Structure of PDB 1h3m Chain A

Receptor sequence
>1h3mA (length=215) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
LDVCAVVPAACPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSR
FAQLPLANHPQITVVDGGDERADSVLTGLKAAGDAQWVLVHDAARPCLHQ
DDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHAL
TPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKV
TRPEDLALAEFYLTR
3D structure
PDB1h3m Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N2P A R143 H153 V155 R129 H139 V141
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0016779 nucleotidyltransferase activity
GO:0042802 identical protein binding
GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO:0070567 cytidylyltransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:1h3m, PDBe:1h3m, PDBj:1h3m
PDBsum1h3m
PubMed12595740
UniProtQ46893|ISPD_ECOLI 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (Gene Name=ispD)

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