Structure of PDB 1h3d Chain A

Receptor sequence
>1h3dA (length=288) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
TRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVR
DDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGC
RLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGS
VEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEE
SKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTIL
PLAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
3D structure
PDB1h3d The Structure of Escherichia Coli ATP-Phosphoribosyltransferase: Identification of Substrate Binding Sites and Mode of AMP Inhibition
ChainA
Resolution2.7 Å
3D
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A R16 E156 D169 L170 S172 T173 G174 A175 T176 R12 E152 D165 L166 S168 T169 G170 A171 T172
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h3d, PDBe:1h3d, PDBj:1h3d
PDBsum1h3d
PubMed14741209
UniProtP60757|HIS1_ECOLI ATP phosphoribosyltransferase (Gene Name=hisG)

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