Structure of PDB 1gz1 Chain A

Receptor sequence
>1gz1A (length=362) Species: 34413 (Humicola insolens) [Search protein sequence]
YAGNPFEGVQLWANNYYRSEVHTLAIPQITDPALRAAASAVAEVPSFQWL
DRNVTVDTLLVQTLSEIREANQAGANPQYAAQIVVYDLPDRDCAAAASNG
EWAIANNGVNNYKAYINRIREILISFSDVRTILVIEPDSLANMVTNMNVP
KCSGAASTYRELTIYALKQLDLPHVAMYMDAGHAGWLGWPANIQPAAELF
AKIYEDAGKPRAVRGLATNVANYNAWSVSSPPPYTSPNPNYDEKHYIEAF
RPLLEARGFPAQFIVDQGRSGKQPTGQKEWGHWCNAIGTGFGMRPTANTG
HQYVDAFVWVKPGGECDGTSDTTAARYAYHCGLEDALKPAPEAGQWFNEY
FIQLLRNANPPF
3D structure
PDB1gz1 Structure of the Humicola Insolens Cellobiohydrolase Cel6A D416A Mutant in Complex with a Non-Hydrolysable Substrate Analogue, Methyl Cellobiosyl-4-Thio-Beta-Cellobioside, at 1.9 A
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y174 R179 D180 S186 D226 D405
Catalytic site (residue number reindexed from 1) Y86 R91 D92 S98 D138 D317
Enzyme Commision number 3.2.1.91: cellulose 1,4-beta-cellobiosidase (non-reducing end).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MGL A N234 H271 W274 N146 H183 W186
BS02 SGC A N310 W371 N222 W283
BS03 BGC A Y174 A309 W371 K399 D405 Y86 A221 W283 K311 D317
BS04 BGC A W137 D139 K399 P400 E403 G432 W49 D51 K311 P312 E315 G344
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030245 cellulose catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1gz1, PDBe:1gz1, PDBj:1gz1
PDBsum1gz1
PubMed12454501
UniProtQ9C1S9|GUX6_HUMIN Exoglucanase-6A (Gene Name=cel6A)

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