Structure of PDB 1gxc Chain A

Receptor sequence
>1gxcA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
3D structure
PDB1gxc Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R117 D118 Y136 R137 T138 S140 K141 N166 S192 R26 D27 Y45 R46 T47 S49 K50 N75 S101
External links
PDB RCSB:1gxc, PDBe:1gxc, PDBj:1gxc
PDBsum1gxc
PubMed12049740
UniProtO96017|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)

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