Structure of PDB 1gwn Chain A

Receptor sequence
>1gwnA (length=179) Species: 10090 (Mus musculus) [Search protein sequence]
VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRI
ELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEI
QEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGA
ATYIECSALQSENSVRDIFHVATLACVNK
3D structure
PDB1gwn Crystal Structure of the Core Domain of Rhoe/Rnd3: A Constitutively Activated Small G Protein
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A S32 Q33 G35 K36 T37 A38 F48 Y52 T55 G80 K136 D138 L139 L180 S11 Q12 G14 K15 T16 A17 F27 Y31 T34 G59 K115 D117 L118 L159
BS02 MG A T37 T55 T16 T34
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:1gwn, PDBe:1gwn, PDBj:1gwn
PDBsum1gwn
PubMed12009891
UniProtP61588|RND3_MOUSE Rho-related GTP-binding protein RhoE (Gene Name=Rnd3)

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