Structure of PDB 1gwe Chain A

Receptor sequence
>1gweA (length=498) Species: 1270 (Micrococcus luteus) [Search protein sequence]
TTPHATGSTRQNGAPAVSDRQSLTVGSEGPIVLHDTHLLETHQHFNRMNI
PERRPHAKGSGAFGEFEVTEDVSKYTKALVFQPGTKTETLLRFSTVAGEL
GSPDTWRDVRGFALRFYTEEGNYDLVGNNTPIFFLRDPMKFTHFIRSQKR
LPDSGLRDATMQWDFWTNNPESAHQVTYLMGPRGLPRTWREMNGYGSHTY
LWVNAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENADFHRQDLFESIA
KGDHPKWDLYIQAIPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTLNR
NPENHFAQIESAAFSPSNTVPGIGLSPDRMLLGRAFAYHDAQLYRVGAHV
NQLPVNRPKNAVHNYAFEGQMWYDHTGDRSTYVPNSNGDSWSDETGPVDD
GWEADGTLTREAQALRADDDDFGQAGTLVREVFSDQERDDFVETVAGALK
GVRQDVQARAFEYWKNVDATIGQRIEDEVKRHEGDGIPGVEAGGEARI
3D structure
PDB1gwe The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex.
ChainA
Resolution0.88 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H61 N133 S320
Catalytic site (residue number reindexed from 1) H56 N128 S315
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A R58 R59 P60 H61 R97 A118 V131 G132 N133 F146 S202 F319 M335 R339 Y343 Q347 R350 R53 R54 P55 H56 R92 A113 V126 G127 N128 F141 S197 F314 M330 R334 Y338 Q342 R345
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1gwe, PDBe:1gwe, PDBj:1gwe
PDBsum1gwe
PubMed12454454
UniProtP29422|CATA_MICLU Catalase (Gene Name=katA)

[Back to BioLiP]