Structure of PDB 1gsl Chain A

Receptor sequence
>1gslA (length=243) Species: 3850 (Griffonia simplicifolia) [Search protein sequence]
QNTVNFTYPDFWSYSLKNGTEITFLGDATRIPGALQLTKTDANGNPVRSS
AGQASYSEPVFLWDSTGKAASFYTSFTFLLKNYGAPTADGLAFFLAPVDS
SVKDYGGFLGLFRHETAADPSKNQVVAVEFDTWINKDWNDPPYPHIGIDV
NSIVSVATTRWENDDAYGSSIATAHITYDARSKILTVLLSYEHGRDYILS
HVVDLAKVLPQKVRIGFSAGVGYDEVTYILSWHFFSTLDGTNK
3D structure
PDB1gsl Structures of the lectin IV of Griffonia simplicifolia and its complex with the Lewis b human blood group determinant at 2.0 A resolution.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL A D89 G107 W133 N135 Y223 D89 G107 W133 N135 Y223
BS02 FUC A F108 H114 W138 F108 H114 W138
BS03 FUC A R48 S49 Y105 G222 R48 S49 Y105 G222
BS04 FUC A L25 G26 L25 G26
BS05 MN A E129 D131 D140 H145 E129 D131 D140 H145
BS06 CA A D131 W133 N135 D140 D131 W133 N135 D140
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1gsl, PDBe:1gsl, PDBj:1gsl
PDBsum1gsl
PubMed8478943
UniProtP24146|LEC4_GRISI Lectin-4

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