Structure of PDB 1gni Chain A

Receptor sequence
>1gniA (length=582) Species: 9606 (Homo sapiens) [Search protein sequence]
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKT
CVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECF
LQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAP
ELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCAS
LQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLE
CADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADL
PSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKT
YETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYK
FQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDY
LSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEF
NAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFA
AFVEKCCKADDKETCFAEEGKKLVAASQAALG
3D structure
PDB1gni Crystal Structures of Human Serum Albumin Complexed with Monounsaturated and Polyunsaturated Fatty Acids.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OLA A R117 Y138 F157 A158 Y161 G189 R115 Y136 F155 A156 Y159 G187 MOAD: Kd=8.5nM
PDBbind-CN: -logKd/Ki=8.07,Kd=8.5nM
BS02 OLA A V46 Y150 A254 R257 S287 V44 Y148 A252 R255 S285 MOAD: Kd=8.5nM
PDBbind-CN: -logKd/Ki=8.07,Kd=8.5nM
BS03 OLA A S342 R348 I388 C392 G434 R485 S340 R346 I386 C390 G432 R483 MOAD: Kd=8.5nM
PDBbind-CN: -logKd/Ki=8.07,Kd=8.5nM
BS04 OLA A Y411 V418 S419 T422 L460 L463 F488 S489 Y409 V416 S417 T420 L458 L461 F486 S487 MOAD: Kd=8.5nM
PDBbind-CN: -logKd/Ki=8.07,Kd=8.5nM
BS05 OLA A Y401 K525 H535 M548 F551 Q580 Y399 K523 H533 M546 F549 Q578 MOAD: Kd=8.5nM
PDBbind-CN: -logKd/Ki=8.07,Kd=8.5nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005504 fatty acid binding
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0015643 toxic substance binding
GO:0016209 antioxidant activity
GO:0019825 oxygen binding
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0051087 protein-folding chaperone binding
GO:0140272 exogenous protein binding
GO:1903981 enterobactin binding
Biological Process
GO:0009267 cellular response to starvation
GO:0051902 negative regulation of mitochondrial depolarization
GO:0072732 cellular response to calcium ion starvation
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0031093 platelet alpha granule lumen
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1gni, PDBe:1gni, PDBj:1gni
PDBsum1gni
PubMed11743713
UniProtP02768|ALBU_HUMAN Albumin (Gene Name=ALB)

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