Structure of PDB 1gky Chain A

Receptor sequence
>1gkyA (length=186) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SRPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVNGKDY
NFVSVDEFKSMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDID
MQGVKSVKAIPELNARFLFIAPPSVEDLKKRLEGRGTETEESINKRLSAA
QAELAYAETGAHDKVIVNDDLDKAYKELKDFIFAEK
3D structure
PDB1gky Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.8: guanylate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A G11 G13 K14 S15 G11 G13 K14 S15
BS02 5GP A S34 R38 R41 Y50 E69 Y78 G79 S80 I99 D100 S34 R38 R41 Y50 E69 Y78 G79 S80 I99 D100
Gene Ontology
Molecular Function
GO:0004385 guanylate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0006163 purine nucleotide metabolic process
GO:0016310 phosphorylation
GO:0046037 GMP metabolic process
GO:0046711 GDP biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1gky, PDBe:1gky, PDBj:1gky
PDBsum1gky
PubMed1314905
UniProtP15454|KGUA_YEAST Guanylate kinase (Gene Name=GUK1)

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