Structure of PDB 1gji Chain A

Receptor sequence
>1gjiA (length=275) Species: 9031 (Gallus gallus) [Search protein sequence]
PYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFG
KVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGI
QCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLP
DEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFIL
CDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPI
TVKMQLRRPSDQEVSEPMDFRYLPD
3D structure
PDB1gji X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2.
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y24 C26 K110 K111 R178 P180 Q211 K212 Q238 Y18 C20 K104 K105 R172 P174 Q205 K206 Q232 PDBbind-CN: Kd=25nM
BS02 dna A R21 R23 S30 R15 R17 S24 PDBbind-CN: Kd=25nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1gji, PDBe:1gji, PDBj:1gji
PDBsum1gji
PubMed11587641
UniProtP16236|REL_CHICK Proto-oncogene c-Rel (Gene Name=REL)

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