Structure of PDB 1g7t Chain A

Receptor sequence
>1g7tA (length=569) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence]
MKIRSPIVSVLGHVDHGKTTLLDHIRGSAVASRITQHIGATEIPMDVIEG
ICGDFLKKFSIRETLPGLFFIDTPGHEAFTTLRKRGGALADLAILIVDIN
EGFKPQTQEALNILRMYRTPFVVAANKIDRIHGWRVHEGRPFMETFSKQD
IQVQQKLDTKVYELVGKLHEEGFESERFDRVTDFASQVSIIPISAITGEG
IPELLTMLMGLAQQYLREQLKIEEDSPARGTILEVKEETGLGMTIDAVIY
DGILRKDDTIAMMTSKDVISTRIRSLLKPRPSRKKFQKVDEVVAAAGIKI
VAPGIDDVMAGSPLRVVTDPEKVREEILSEIEDIKIDTDEAGVVVKADTL
GSLEAVVKILRDMYVPIKVADIGDVSRRDVVNAGIALQEDRVYGAIIAFN
VKVIPSAAQELKNSDIKLFQGNVIYRLMEEYEEWVRGIEEEKKKKWMEAI
IKPASIRLIPKLVFRQSKPAIGGVEVLTGVIRQGYPLMNDDGETVGTVES
MQDKGENLKSASRGQKVAMAIKDAVYGKTIHEGDTLYVDIPENHYHILLT
DEELDLMDKIAEIKRKKNP
3D structure
PDB1g7t X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D15
Catalytic site (residue number reindexed from 1) D15
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A D15 G17 K18 T19 T20 E81 N130 K131 D133 R134 S198 A199 I200 D15 G17 K18 T19 T20 E77 N126 K127 D129 R130 S194 A195 I196
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1g7t, PDBe:1g7t, PDBj:1g7t
PDBsum1g7t
PubMed11114334
UniProtO26359|IF2P_METTH Probable translation initiation factor IF-2 (Gene Name=infB)

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