Structure of PDB 1g5f Chain A

Receptor sequence
>1g5fA (length=294) Species: 13689 (Sphingomonas paucimobilis) [Search protein sequence]
LGAKPFGEKKFIEIKGRRMAYIDEGTGDPILFQHGNPTSSYLWRNIMPHC
AGLGRLIACDLIGMGDSDKLDPSGPERYAYAEHRDYLDALWEALDLGDRV
VLVVHDWGSALGFDWARRHRERVQGIAYMEAIAMPIEWADFPEQDRDLFQ
AFRSQAGEELVLQDNVFVEQVLPGLILRPLSEAEMAAYREPFLAAGEARR
PTLSWPRQIPIAGTPADVVAIARDYAGWLSESPIPKLFINAEPGALTTGR
MRDFCRTWPNQTEITVAGAHFIQEDSPDEIGAAIAAFVRRLRPA
3D structure
PDB1g5f Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N38 D108 W109 E132 F143 G246 H272
Catalytic site (residue number reindexed from 1) N36 D106 W107 E130 F141 G244 H270
Enzyme Commision number 3.8.1.5: haloalkane dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A P175 I178 P173 I176
BS02 DCE A F151 H272 F149 H270 MOAD: Ki=2.31mM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018786 haloalkane dehalogenase activity
Biological Process
GO:0009636 response to toxic substance
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Cellular Component
External links
PDB RCSB:1g5f, PDBe:1g5f, PDBj:1g5f
PDBsum1g5f
PubMed11939779
UniProtD4Z2G1|LINB_SPHIU Haloalkane dehalogenase (Gene Name=linB)

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