Structure of PDB 1g0d Chain A

Receptor sequence
>1g0dA (length=666) Species: 143350 (Pagrus major) [Search protein sequence]
GLIVDVNGRSHENNLAHRTREIDRERLIVRRGQPFSITLQCSDSLPPKHH
LELVLHLGKRDEVVIKVQKEHGARDKWWFNQQGAQDEILLTLHSPANAVI
GHYRLAVLVMSPDGHIVERADKISFHMLFNPWCRDDMVYLPDESKLQEYV
MNEDGVIYMGTWDYIRSIPWNYGQFEDYVMDICFEVLDNSPAALKNSEMD
IEHRSDPVYVGRTITAMVNSNGDRGVLTGRWEEPYTDGVAPYRWTGSVPI
LQQWSKAGVRPVKYGQCWVFAAVACTVLRCLGIPTRPITNFASAHDVDGN
LSVDFLLNERLESLDSRQRSDSSWNFHCWVESWMSREDLPEGNDGWQVLD
PTPQELSDGEFCCGPCPVAAIKEGNLGVKYDAPFVFAEVNADTIYWIVQK
DGQRRKITEDHASVGKNISTKSVYGNHREDVTLHYKYPEGSQKEREVYKK
AGRRVTRLQLSIKHAQPVFGTDFDVIVEVKNEGGRDAHAQLTMLAMAVTY
NSLRRGECQRKTISVTVPAHKAHKEVMRLHYDDYVRCVSEHHLIRVKALL
DAPGPIMTVANIPLSTPELLVQVPGKAVVWEPLTAYVSFTNPLPVPLKGG
VFTLEGAGLLSATQIHVNGAVAPSGKVSVKLSFSPMRTGVRKLLVDFDSD
RLKDVKGVTTVVVHKK
3D structure
PDB1g0d Crystal structure of red sea bream transglutaminase.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) W236 C272 H332 D355 Y515
Catalytic site (residue number reindexed from 1) W231 C267 H327 D350 Y500
Enzyme Commision number 2.3.1.-
2.3.2.13: protein-glutamine gamma-glutamyltransferase.
3.4.-.-
3.5.1.44: protein-glutamine glutaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A K150 R291 W351 H439 K145 R286 W346 H434
Gene Ontology
Molecular Function
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0005509 calcium ion binding
GO:0005525 GTP binding
GO:0008233 peptidase activity
GO:0016746 acyltransferase activity
GO:0046872 metal ion binding
GO:0050568 protein-glutamine glutaminase activity
GO:0120294 peptide serotonyltransferase activity
GO:0120295 histone serotonyltransferase activity
GO:0120296 peptide dopaminyltransferase activity
GO:0120297 histone dopaminyltransferase activity
GO:0120298 peptide noradrenalinyltransferase activity
GO:0120299 peptide histaminyltransferase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006508 proteolysis
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007399 nervous system development
GO:0018149 peptide cross-linking
GO:0018277 protein deamination
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051260 protein homooligomerization
GO:0060348 bone development
GO:1903351 cellular response to dopamine
GO:1904015 cellular response to serotonin
GO:2000425 regulation of apoptotic cell clearance
Cellular Component
GO:0000785 chromatin
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0062023 collagen-containing extracellular matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1g0d, PDBe:1g0d, PDBj:1g0d
PDBsum1g0d
PubMed11080504
UniProtP52181|TGM2_PAGMA Protein-glutamine gamma-glutamyltransferase 2 (Gene Name=tgm2)

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