Structure of PDB 1fyr Chain A

Receptor sequence
>1fyrA (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQH
FKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
3D structure
PDB1fyr Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R67 R86 S88 E89 S90 S96 H107 F108 K109 W121 R10 R29 S31 E32 S33 S39 H50 F51 K52 W64
External links
PDB RCSB:1fyr, PDBe:1fyr, PDBj:1fyr
PDBsum1fyr
PubMed11063574
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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