Structure of PDB 1fyn Chain A

Receptor sequence
>1fynA (length=62) Species: 9606 (Homo sapiens) [Search protein sequence]
GTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGET
GYIPSNYVAPVD
3D structure
PDB1fyn High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y91 R96 E116 W119 Y132 N136 Y137 Y11 R16 E36 W39 Y52 N56 Y57
External links
PDB RCSB:1fyn, PDBe:1fyn, PDBj:1fyn
PDBsum1fyn
PubMed7664083
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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