Structure of PDB 1fx8 Chain A

Receptor sequence
>1fx8A (length=254) Species: 562 (Escherichia coli) [Search protein sequence]
TLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEISVIWGLGVAMA
IYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVY
GLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVI
TAILMGLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPA
RDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLI
GRHL
3D structure
PDB1fx8 Structure of a glycerol-conducting channel and the basis for its selectivity.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL A W48 G199 F200 A201 R206 W43 G194 F195 A196 R201
BS02 GOL A N68 N203 N63 N198
Gene Ontology
Molecular Function
GO:0005372 water transmembrane transporter activity
GO:0015168 glycerol transmembrane transporter activity
GO:0015254 glycerol channel activity
GO:0015267 channel activity
Biological Process
GO:0006833 water transport
GO:0015791 polyol transmembrane transport
GO:0015793 glycerol transmembrane transport
GO:0055085 transmembrane transport
GO:0071288 cellular response to mercury ion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:1fx8, PDBe:1fx8, PDBj:1fx8
PDBsum1fx8
PubMed11039922
UniProtP0AER0|GLPF_ECOLI Glycerol uptake facilitator protein (Gene Name=glpF)

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