Structure of PDB 1fwz Chain A

Receptor sequence
>1fwzA (length=211) Species: 1717 (Corynebacterium diphtheriae) [Search protein sequence]
LVDTTEMYLRTIYELEAEGVTPLRARIAERLEQSGPTVSQTVARMERDGL
VVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEACR
WEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVPGTRVIDAATSMP
RKVRIVQINEIFQVETDQFTQLLDADIRVGSEVEIVDRHITLSHNGKDVE
LLDDLAHTIRI
3D structure
PDB1fwz Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A H79 R80 E83 H98 S126 H76 R77 E80 H95 S123
BS02 ZN A H79 E83 H98 H76 E80 H95
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0017124 SH3 domain binding
GO:0042802 identical protein binding
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1fwz, PDBe:1fwz, PDBj:1fwz
PDBsum1fwz
PubMed11320302
UniProtP0DJL7|DTXR_CORDI Diphtheria toxin repressor (Gene Name=dtxR)

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