Structure of PDB 1fq9 Chain A

Receptor sequence
>1fq9A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
HFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSI
KGVSANRYLAMKEDGRLLASKSVTDECFFFERLESNNYNTYRSRKYTSWY
VALKRTGQYKLGSKTGPGQKAILFLPMSA
3D structure
PDB1fq9 Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGN A K119 K129 K104 K114
BS02 IDS A N27 K119 R120 K125 N12 K104 R105 K110
BS03 SGN A R120 Q134 K135 A136 R105 Q119 K120 A121
BS04 IDS A R120 K135 R105 K120
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1fq9, PDBe:1fq9, PDBj:1fq9
PDBsum1fq9
PubMed11030354
UniProtP09038|FGF2_HUMAN Fibroblast growth factor 2 (Gene Name=FGF2)

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