Structure of PDB 1fn9 Chain A

Receptor sequence
>1fn9A (length=365) Species: 10891 (Reovirus sp.) [Search protein sequence]
MEVCLPNGHQVVDLINNAFEGRVSIYSAQEGWDKTISAQPDMMVCGGAVV
CMHCLGVVGSLQRKLKHLPHHRCNQQIRHQDYVDVQFADRVTAHWKRGML
SFVAQMHEMMNDVSPDDLDRVRTEGGSLVELNWLQVDPNSMFRSIHSSWT
DPLQVVDDLDTKLDQYWTALNLMIDSSDLIPNFMMRDPSHAFNGVKLGGD
ARQTQFSRTFDSRSSLEWGVMVYDYSELEHDPSKGRAYRKELVTPARDFG
HFGLSHYSRATTPILGKMPAVFSGMLTGNCKMYPFIKGTAKLKTVRKLVE
AVNHAWGVEKIRYALGPGGMTGWYNRTMQQAPIVLTPAALTMFPDTIKFG
DLNYPVMIGDPMILG
3D structure
PDB1fn9 Structure of the reovirus outer capsid and dsRNA-binding protein sigma3 at 1.8 A resolution.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C51 C54 H71 C73 C51 C54 H71 C73
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0030291 protein serine/threonine kinase inhibitor activity
GO:0046872 metal ion binding
Biological Process
GO:0006417 regulation of translation
GO:0019049 virus-mediated perturbation of host defense response
GO:0019058 viral life cycle
GO:0039502 symbiont-mediated suppression of host type I interferon-mediated signaling pathway
GO:0039580 symbiont-mediated suppression of host PKR/eIFalpha signaling
GO:0052170 symbiont-mediated suppression of host innate immune response
Cellular Component
GO:0019028 viral capsid
GO:0030430 host cell cytoplasm
GO:0039624 viral outer capsid
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fn9, PDBe:1fn9, PDBj:1fn9
PDBsum1fn9
PubMed11230122
UniProtP03527|SIGM3_REOVD Outer capsid protein sigma-3 (Gene Name=S4)

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