Structure of PDB 1fmw Chain A

Receptor sequence
>1fmwA (length=738) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGE
IVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPA
VFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEV
APHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG
RGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFISGAS
IQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYL
NQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNI
KFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQ
HLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISG
FEIFKVNSFEQLCINYTNEKLQQFFNHHMFKVEQEEYLKEKIDSQATIDL
IDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKT
EFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPN
IASRAFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKV
VLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQK
ATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEARE
3D structure
PDB1fmw X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain.
ChainA
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S180 G181 T185 N226 S229 S230 G450 E452
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T185 S230
BS02 ATP A N127 P128 Y135 S181 G182 G184 K185 T186 E187 N233 S236 S237 N126 P127 Y134 S180 G181 G183 K184 T185 E186 N226 S229 S230
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1fmw, PDBe:1fmw, PDBj:1fmw
PDBsum1fmw
PubMed10954715
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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