Structure of PDB 1fhw Chain A

Receptor sequence
>1fhwA (length=122) Species: 10090 (Mus musculus) [Search protein sequence]
PDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLS
IREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPS
PEEKEEWMKSIKASISRDPFYD
3D structure
PDB1fhw Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I5P A K273 G276 R277 K282 R284 Y295 R305 K343 H355 K9 G12 R13 K18 R20 Y31 R41 K79 H91 MOAD: Kd=0.33uM
External links
PDB RCSB:1fhw, PDBe:1fhw, PDBj:1fhw
PDBsum1fhw
PubMed10983984
UniProtO08967|CYH3_MOUSE Cytohesin-3 (Gene Name=Cyth3)

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