Structure of PDB 1fhe Chain A

Receptor sequence
>1fheA (length=214) Species: 6192 (Fasciola hepatica) [Search protein sequence]
PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLD
LPNLPYYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMD
LRIGFGRVCYNPKFEEVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHV
DFMLYETLDSIRYLAPHCLDEFPKLKEFKSRIEALPKIKAYMESKRFIKW
PLNGWAASFGAGDA
3D structure
PDB1fhe Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase.
ChainA
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y6 L12 R17
Catalytic site (residue number reindexed from 1) Y6 L12 R17
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A K44 N53 L54 Q66 K44 N53 L54 Q66
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fhe, PDBe:1fhe, PDBj:1fhe
PDBsum1fhe
PubMed9367777
UniProtP31670|GST27_FASHE Glutathione S-transferase class-mu 26 kDa isozyme 47

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