Structure of PDB 1ff5 Chain A

Receptor sequence
>1ff5A (length=219) Species: 10090 (Mus musculus) [Search protein sequence]
MDWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVG
VFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVT
DQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYT
IVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGE
GLSTTAKAVITVKDINDNA
3D structure
PDB1ff5 A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation.
ChainA
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N102 N104 D134 D136 N143 D195 N103 N105 D135 D137 N144 D196
BS02 CA A E11 E69 D100 Q101 D103 D136 E12 E70 D101 Q102 D104 D137
BS03 CA A E11 N12 D67 D103 E12 N13 D68 D104
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ff5, PDBe:1ff5, PDBj:1ff5
PDBsum1ff5
PubMed10202138
UniProtP09803|CADH1_MOUSE Cadherin-1 (Gene Name=Cdh1)

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