Structure of PDB 1fdq Chain A

Receptor sequence
>1fdqA (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
VEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVV
IRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGK
ETNFVREIKDGKMVMTLTFGDVVAVRHYEKA
3D structure
PDB1fdq Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HXA A V40 T60 E72 T74 A75 D76 M115 R126 Y128 V40 T60 E72 T74 A75 D76 M115 R126 Y128 MOAD: Kd=53.4nM
PDBbind-CN: -logKd/Ki=7.27,Kd=53.4nM
Gene Ontology
Molecular Function
GO:0005504 fatty acid binding
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0007399 nervous system development
GO:0008285 negative regulation of cell population proliferation
GO:0015908 fatty acid transport
GO:0050673 epithelial cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1fdq, PDBe:1fdq, PDBj:1fdq
PDBsum1fdq
PubMed10854433
UniProtO15540|FABP7_HUMAN Fatty acid-binding protein, brain (Gene Name=FABP7)

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