Structure of PDB 1fch Chain A

Receptor sequence
>1fchA (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
SATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDP
KHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNE
SLQRQACEILRDWLRYTPAYAHLVTRILGSLLSDSLFLEVKELFLAAVRL
DPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGAT
LANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLE
ALNMQRKSGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGL
PQ
3D structure
PDB1fch Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V374 N378 N489 K490 A493 N497 R520 N524 I527 N531 L572 V95 N99 N195 K196 A199 N203 R226 N230 I233 N237 L272
BS02 peptide A D468 K469 V471 D472 Q500 D174 K175 V177 D178 Q206
External links
PDB RCSB:1fch, PDBe:1fch, PDBj:1fch
PDBsum1fch
PubMed11101887
UniProtP50542|PEX5_HUMAN Peroxisomal targeting signal 1 receptor (Gene Name=PEX5)

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