Structure of PDB 1fbz Chain A

Receptor sequence
>1fbzA (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFCLSVRDFDQ
NQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSR
PCQT
3D structure
PDB1fbz Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CC1 A R12 R32 S36 H58 Y59 K60 I71 G93 R12 R32 S36 H58 Y59 K60 I71 G93
External links
PDB RCSB:1fbz, PDBe:1fbz, PDBj:1fbz
PDBsum1fbz
PubMed10944210
UniProtP06239|LCK_HUMAN Tyrosine-protein kinase Lck (Gene Name=LCK)

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