Structure of PDB 1fao Chain A

Receptor sequence
>1faoA (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
PSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLT
ECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQI
3D structure
PDB1fao Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4IP A K173 G175 G176 L177 V178 T180 R184 Y195 I205 R235 K12 G14 G15 L16 V17 T19 R23 Y34 I44 R74 MOAD: Kd=0.043uM
PDBbind-CN: -logKd/Ki=7.37,Kd=0.043uM
External links
PDB RCSB:1fao, PDBe:1fao, PDBj:1fao
PDBsum1fao
PubMed10983984
UniProtQ9UN19|DAPP1_HUMAN Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (Gene Name=DAPP1)

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