Structure of PDB 1f8v Chain A

Receptor sequence
>1f8vA (length=355) Species: 103782 (Pariacoto virus) [Search protein sequence]
NRRNKARKVVSRSTALVPMAPASQRTGPAPRKPRKRNQALVRNPRLTDAG
LAFLKCAFAAPDFSVDPGKGIPDNFHGRTLAIKDCNTTSVVFTPNTDTYI
VVAPVPGFAYFRAEVAVGAQPTTFVGVPYPTYATNFGAGSQNGLPAVNNY
SKFRYASMACGLYPTSNMMQFSGSVQVWRVDLNLSEAVNPAVTAITPAPG
VFANFVDKRINGLRGIRPLAPRDNYSGNFIDGAYTFAFDKSTDFEWCDFV
RSLEFSESNVLGAATAMKLLAPGGGTDTTLTGLGNVNTLVYKISTPTGAV
NTAILRTWNCIELQPYTDSALFQFSGVSPPFDPLALECYHNLKMRFPVAV
SSREN
3D structure
PDB1f8v The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.44: nodavirus endopeptidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K11 R13 K5 R7
BS02 peptide A R48 K61 F64 A65 D68 P339 E343 C344 L348 R351 N361 R42 K55 F58 A59 D62 P333 E337 C338 L342 R345 N355
BS03 peptide A P39 R40 R42 L46 V47 R48 P50 P33 R34 R36 L40 V41 R42 P44
BS04 peptide A V47 R48 N49 V41 R42 N43
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:1f8v, PDBe:1f8v, PDBj:1f8v
PDBsum1f8v
PubMed11135676
UniProtQ9J7Z0|CAPSD_PAV Capsid protein alpha (Gene Name=alpha)

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