Structure of PDB 1f6u Chain A

Receptor sequence
>1f6uA (length=55) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
MQKGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKDCT
ERQAN
3D structure
PDB1f6u NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K3 Q9 K14 F16 I24 A25 K26 N27 R32 G35 C36 W37 Q45 M46 K3 Q9 K14 F16 I24 A25 K26 N27 R32 G35 C36 W37 Q45 M46 PDBbind-CN: Kd=110nM
BS02 ZN A C15 C18 H23 C28 N55 C15 C18 H23 C28 N55
BS03 ZN A C36 C39 H44 C49 C36 C39 H44 C49
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:1f6u, PDBe:1f6u, PDBj:1f6u
PDBsum1f6u
PubMed10926523
UniProtP35963|POL_HV1Y2 Gag-Pol polyprotein (Gene Name=gag-pol)

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