Structure of PDB 1f5t Chain A

Receptor sequence
>1f5tA (length=120) Species: 1717 (Corynebacterium diphtheriae) [Search protein sequence]
KDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERD
GLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEA
DRWEHVMSDEVERRLVKVLK
3D structure
PDB1f5t Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R1027 A1028 R1029 S1042 R1060 R26 A27 R28 S41 R59 PDBbind-CN: Kd=460nM
BS02 dna A K1002 T1007 Q1036 S1037 P1039 T1040 Q1043 R1047 R1050 K1 T6 Q35 S36 P38 T39 Q42 R46 R49 PDBbind-CN: Kd=460nM
BS03 NI A M1010 D1102 E1105 H1106 M9 D101 E104 H105
BS04 NI A H1079 E1083 H1098 H78 E82 H97
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1f5t, PDBe:1f5t, PDBj:1f5t
PDBsum1f5t
PubMed10956029
UniProtP0DJL7|DTXR_CORDI Diphtheria toxin repressor (Gene Name=dtxR)

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