Structure of PDB 1f5f Chain A

Receptor sequence
>1f5fA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
PPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNP
KDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSV
LLEVDGEEVLRLRQVSGPLHPIMRIALGGLLFPASNLRLPLVPALDGCLR
RDSWLDKQAEISASAPTSLRSC
3D structure
PDB1f5f Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D50 E52 A160 D38 E40 A144
BS02 ZN A D65 H83 H136 D53 H71 H120
BS03 ZN A H101 D117 H89 D105
BS04 DHT A S41 S42 D65 F67 N82 V105 M107 S29 S30 D53 F55 N70 V93 M95 BindingDB: IC50=3.8nM,Kd=0.182000nM
External links
PDB RCSB:1f5f, PDBe:1f5f, PDBj:1f5f
PDBsum1f5f
PubMed10859323
UniProtP04278|SHBG_HUMAN Sex hormone-binding globulin (Gene Name=SHBG)

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