Structure of PDB 1f44 Chain A

Receptor sequence

>1f44A (length=316) Species: 10678 (Punavirus P1) [Search protein sequence]

SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRGVEKALSLGVTKLVERWISV
SGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKD
DSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNIVMNFIRN
LDSETGAMVRLLEDGD

3D structure

PDB

1f44 Quasi-equivalence in site-specific recombinase structure and function: crystal structure and activity of trimeric Cre recombinase bound to a three-way Lox DNA junction.

Chain

Resolution

2.05 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	K43 M44 S47 R50 R81 L83 A84 K86 T87 Q90 A131 K132 Q133 R159 R241 V242 K244 S257 R259 A260 R282 R292 W315 I320 R326	K24 M25 S28 R31 R62 L64 A65 K67 T68 Q71 A112 K113 Q114 R140 R214 V215 K217 S230 R232 A233 R255 R265 W288 I293 R299
BS02	dna	A	S38 H40 T41 R100 R121 R173 I174 A175 R243 K244 N245 R259 E262 K276 R282 Y283 S287 G288 H289	S19 H21 T22 R81 R102 R154 I155 A156 R216 K217 N218 R232 E235 K249 R255 Y256 S260 G261 H262

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:1f44, PDBe:1f44, PDBj:1f44
PDBsum	1f44
PubMed	11601846
UniProt	P06956\|RECR_BPP1 Recombinase cre (Gene Name=cre)

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