Structure of PDB 1exm Chain A

Receptor sequence
>1exmA (length=403) Species: 274 (Thermus thermophilus) [Search protein sequence]
GEFIRTKPHVNVGTIGHVDHGKTTLTAALTFVTAAENPNVEVKDYGDIDK
APEERARGITINTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGA
ILVVSAADGPMPQTREHILLARQVGVPYIVVFMNKVDMVDDPELLDLVEM
EVRDLLNQYEFPGDEVPVIRGSALLALEQMHRNPKTRRGENEWVDKIWEL
LDAIDEYIPTPVRDVDKPFLMPVEDVFTITGRGTVATGRIERGKVKVGDE
VEIVGLAPETRKTVVTGVEMHRKTLQEGIAGDNVGVLLRGVSREEVERGQ
VLAKPGSITPHTKFEASVYVLKKEEGGRHTGFFSGYRPQFYFRTTDVTGV
VQLPPGVEMVMPGDNVTFTVELIKPVALEEGLRFAIREGGRTVGAGVVTK
ILE
3D structure
PDB1exm REGULATORY GTPASES
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 K24 T25 T62 H85
Catalytic site (residue number reindexed from 1) D19 K22 T23 T60 H83
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T25 T62 T23 T60
BS02 GNP A V20 D21 G23 K24 T25 T26 Y47 I61 T62 G84 N136 K137 D139 M140 S174 L176 V18 D19 G21 K22 T23 T24 Y45 I59 T60 G82 N134 K135 D137 M138 S172 L174
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1exm, PDBe:1exm, PDBj:1exm
PDBsum1exm
PubMed
UniProtP60338|EFTU1_THETH Elongation factor Tu-A (Gene Name=tufA)

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