Structure of PDB 1exc Chain A

Receptor sequence
>1excA (length=185) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEENVQWLA
KQKAKAVADLHPHAIVIGADTMVCLDGECLGKPQDQEEAASMLRRLSGRS
HSVITAVSIQAENHSETFYDKTEVAFWSLSEEEIWTYIETKEPMDKAGAY
GIQGRGALFVKKIDGDYYSVMGLPISKTMRALRHF
3D structure
PDB1exc Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.9: nucleotide diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUT A S9 R14 E34 K53 S9 R14 E34 K53
BS02 DUT A W48 K51 K55 W48 K51 K55
Gene Ontology
Molecular Function
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0036218 dTTP diphosphatase activity
GO:0036221 UTP diphosphatase activity
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1exc, PDBe:1exc, PDBj:1exc
PDBsum1exc
PubMed10841541
UniProtQ02169|NTPPA_BACSU dTTP/UTP pyrophosphatase (Gene Name=maf)

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