Structure of PDB 1ex2 Chain A

Receptor sequence
>1ex2A (length=185) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEENVQWLA
KQKAKAVADLHPHAIVIGADTMVCLDGECLGKPQDQEEAASMLRRLSGRS
HSVITAVSIQAENHSETFYDKTEVAFWSLSEEEIWTYIETKEPMDKAGAY
GIQGRGALFVKKIDGDYYSVMGLPISKTMRALRHF
3D structure
PDB1ex2 Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.9: nucleotide diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FRU A V29 S30 E31 V29 S30 E31
BS02 PO4 A S9 R14 K53 S9 R14 K53
BS03 PO4 A K51 K55 K51 K55
Gene Ontology
Molecular Function
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0036218 dTTP diphosphatase activity
GO:0036221 UTP diphosphatase activity
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1ex2, PDBe:1ex2, PDBj:1ex2
PDBsum1ex2
PubMed10841541
UniProtQ02169|NTPPA_BACSU dTTP/UTP pyrophosphatase (Gene Name=maf)

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