Structure of PDB 1ewj Chain A

Receptor sequence
>1ewjA (length=119) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
TDQATPNLPSRDFDSTAAFYERLGFGIVFRDAGWMILQRGDLMLEFFAHP
GLDPLASWFSCCLRLDDLAEFYRQCKSVGIQETSSGYPRIHAPELQEWGG
TMAALVDPDGTLLRLIQNE
3D structure
PDB1ewj Crystal structures of the transposon Tn5-carried bleomycin resistance determinant uncomplexed and complexed with bleomycin.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLM A L56 A57 S58 W59 R65 S86 G87 R90 W99 G111 L113 R115 N119 L55 A56 S57 W58 R64 S85 G86 R89 W98 G110 L112 R114 N118 PDBbind-CN: -logKd/Ki=7.49,Kd=32nM
BS02 BLM A F30 W35 I37 F29 W34 I36 PDBbind-CN: -logKd/Ki=7.49,Kd=32nM
Gene Ontology
Biological Process
GO:0046677 response to antibiotic

View graph for
Biological Process
External links
PDB RCSB:1ewj, PDBe:1ewj, PDBj:1ewj
PDBsum1ewj
PubMed11134052
UniProtP13081|BLE_KLEPN Bleomycin resistance protein (Gene Name=ble)

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