Structure of PDB 1esz Chain A

Receptor sequence
>1eszA (length=260) Species: 562 (Escherichia coli) [Search protein sequence]
IDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVG
LRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLA
MARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTL
IDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKD
VDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAM
HFVRVLDNAI
3D structure
PDB1esz X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CPO A E42 W68 R84 S103 Y106 I183 W217 W273 F274 Y275 E10 W36 R52 S71 Y74 I151 W185 W241 F242 Y243 MOAD: Kd=0.3uM
PDBbind-CN: -logKd/Ki=6.52,Kd=0.3uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0006826 iron ion transport
GO:0015687 ferric-hydroxamate import into cell
GO:0098711 iron ion import across plasma membrane
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Cellular Component
External links
PDB RCSB:1esz, PDBe:1esz, PDBj:1esz
PDBsum1esz
PubMed11805094
UniProtP07822|FHUD_ECOLI Iron(3+)-hydroxamate-binding protein FhuD (Gene Name=fhuD)

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