Structure of PDB 1esd Chain A

Receptor sequence
>1esdA (length=302) Species: 1930 (Streptomyces scabiei) [Search protein sequence]
DPVPTVFFGDSYTANFGIAPVTNQDSERGWCFQAKENYPAVATRSLADKG
ITLDVQADVSCGGALIHHFWEKQELPFGAGELPPQQDALKQDTQLTVGSL
GGNTLGFNRILKQCSDELRKPSLLPGDPVDGDEPAAKCGEFFGTGDGKQW
LDDQFERVGAELEELLDRIGYFAPDAKRVLVGYPRLVPEDTTKCLTAAPG
QTQLPFADIPQDALPVLDQIQKRLNDAMKKAAADGGADFVDLYAGTGANT
ACDGADRGIGGLLEDSQLELLGTKIPWYAHPNDKGRDIQAKQVADKIEEI
LN
3D structure
PDB1esd A novel variant of the catalytic triad in the Streptomyces scabies esterase.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S14 G66 N106 W280 H283
Catalytic site (residue number reindexed from 1) S11 G63 N103 W277 H280
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VXA A S14 N106 H283 S11 N103 H280
Gene Ontology
Molecular Function
GO:0004806 triacylglycerol lipase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0019433 triglyceride catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1esd, PDBe:1esd, PDBj:1esd
PDBsum1esd
PubMed7773790
UniProtP22266|ESTA_STRSC Esterase (Gene Name=estA)

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