Structure of PDB 1eop Chain A

Receptor sequence
>1eopA (length=238) Species: 562 (Escherichia coli) [Search protein sequence]
SLRSDLINALYDEVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIA
EKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFT
LGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINEL
NEIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIF
DSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGR
3D structure
PDB1eop Crystallographic snapshots along a protein-induced DNA-bending pathway.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T37 N70 K92 T93 T94 Y95 T106 T111 K119 N120 S183 T186 N188 T31 N64 K86 T87 T88 Y89 T100 T105 K113 N114 S177 T180 N182
BS02 dna A Q69 S183 G184 N185 S223 R226 Q63 S177 G178 N179 S217 R220
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1eop, PDBe:1eop, PDBj:1eop
PDBsum1eop
PubMed10801972
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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