Structure of PDB 1enc Chain A

Receptor sequence
>1encA (length=135) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LHKEPATLIKAIDGETVKLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGP
EASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQ
GLAKVAYVYKPNNTHEQHLRKSEAQAKKEKLNIWS
3D structure
PDB1enc Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) E15 R29 D34 T35 E37 R81
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E21 D40 E43 E15 D34 E37
BS02 THP A E21 R35 D83 K84 Y85 R87 L89 Y113 Y115 E15 R29 D77 K78 Y79 R81 L83 Y107 Y109
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1enc, PDBe:1enc, PDBj:1enc
PDBsum1enc
PubMed8025105
UniProtP00644|NUC_STAAU Thermonuclease (Gene Name=nuc)

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