Structure of PDB 1emu Chain A

Receptor sequence
>1emuA (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
PPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEP
CDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDP
AMFDQAQTEIQATMEENTYPSFLKSDIYLEYT
3D structure
PDB1emu Structural basis of the Axin-adenomatous polyposis coli interaction.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D131 I136 D153 F156 A157 G160 L177 A180 R183 D15 I20 D37 F40 A41 G44 L61 A64 R67
Gene Ontology
Biological Process
GO:0090090 negative regulation of canonical Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:1emu, PDBe:1emu, PDBj:1emu
PDBsum1emu
PubMed10811618
UniProtO15169|AXIN1_HUMAN Axin-1 (Gene Name=AXIN1)

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