Structure of PDB 1ejh Chain A

Receptor sequence
>1ejhA (length=180) Species: 10090 (Mus musculus) [Search protein sequence]
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQL
SSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWL
ETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR
VYKERLGLPPKIVIGYQSHADTATKNRFVV
3D structure
PDB1ejh Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H37 P38 Q40 V69 W73 N77 E132 G139 R186 H6 P7 Q9 V38 W42 N46 E101 G108 R155
BS02 M7G A W56 M101 W102 E103 R157 K162 W25 M70 W71 E72 R126 K131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ejh, PDBe:1ejh, PDBj:1ejh
PDBsum1ejh
PubMed10394359
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

[Back to BioLiP]