Structure of PDB 1ej4 Chain A

Receptor sequence
>1ej4A (length=179) Species: 10090 (Mus musculus) [Search protein sequence]
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQL
SSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWL
ETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR
VYKERLGLPPKIVIGYQSHADTATNRFVV
3D structure
PDB1ej4 Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A H37 P38 Q40 V69 W73 E132 L135 I138 G139 E140 D147 H6 P7 Q9 V38 W42 E101 L104 I107 G108 E109 D116
BS02 M7G A W56 M101 W102 E103 R157 K159 K162 W25 M70 W71 E72 R126 K128 K131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1ej4, PDBe:1ej4, PDBj:1ej4
PDBsum1ej4
PubMed10394359
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

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