Structure of PDB 1ej2 Chain A

Receptor sequence
>1ej2A (length=167) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence]
MRGLLVGRMQPFHRGHLQVIKSILEEVDELIICIGSAQLSHSIRDPFTAG
ERVMMLTKALSENGIPASRYYIIPVQDIECNALWVGHIKMLTPPFDRVYS
GNPLVQRLFSEDGYEVTAPPLFYRDRYSGTEVRRRMLDDGDWRSLLPESV
VEVIDEINGVERIKHLA
3D structure
PDB1ej2 Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.1: nicotinamide-nucleotide adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A R11 G132 T133 R136 R8 G129 T130 R133
BS02 NAD A V9 G10 R11 G18 H19 G38 S39 D80 I81 N84 W87 S103 G104 N105 L107 L124 F125 Y130 V6 G7 R8 G15 H16 G35 S36 D77 I78 N81 W84 S100 G101 N102 L104 L121 F122 Y127
Gene Ontology
Molecular Function
GO:0000309 nicotinamide-nucleotide adenylyltransferase activity
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009435 NAD biosynthetic process
GO:0019363 pyridine nucleotide biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1ej2, PDBe:1ej2, PDBj:1ej2
PDBsum1ej2
PubMed11063748
UniProtO26253|NADM_METTH Nicotinamide-nucleotide adenylyltransferase (Gene Name=MTH_150)

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