Structure of PDB 1ei1 Chain A

Receptor sequence
>1ei1A (length=391) Species: 562 (Escherichia coli) [Search protein sequence]
SNSSDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEA
LAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAG
GKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQ
APLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLDSGV
SIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIG
VEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEG
YSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQ
QMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
3D structure
PDB1ei1 Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A N46 E50 D73 I78 G101 G102 K103 Y109 G114 L115 H116 G117 V118 G119 V120 T165 K337 N45 E49 D72 I77 G100 G101 K102 Y108 G113 L114 H115 G116 V117 G118 V119 T164 K336
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:1ei1, PDBe:1ei1, PDBj:1ei1
PDBsum1ei1
PubMed10734094
UniProtP0AES6|GYRB_ECOLI DNA gyrase subunit B (Gene Name=gyrB)

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