Structure of PDB 1efx Chain A

Receptor sequence
>1efxA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAVSRPGRGEPHFIAVGYVDDTQFVRFDSDAASPRGEPRAP
WVEQEGPEYWDRETQKYKRQAQTDRVSLRNLRGYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQLRAYLEGLCVEWLRRYLKNGKETLQRAEHPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQWDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPLTLRWEPSS
3D structure
PDB1efx Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 K66 R69 Q70 S77 N80 Y84 Y99 Y116 T143 W147 E152 Y159 W167 Y171 Y7 K66 R69 Q70 S77 N80 Y84 Y99 Y116 T143 W147 E152 Y159 W167 Y171
External links
PDB RCSB:1efx, PDBe:1efx, PDBj:1efx
PDBsum1efx
PubMed10850706
UniProtP10321|HLAC_HUMAN HLA class I histocompatibility antigen, C alpha chain (Gene Name=HLA-C)

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