Structure of PDB 1ecr Chain A

Receptor sequence

>1ecrA (length=305) Species: 37762 (Escherichia coli B) [Search protein sequence]

DLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEVKKEDEHNPLN
RIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDN
LSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLN
AYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWT
REEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHA
CPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLH
LYVAD

3D structure

PDB

1ecr Structure of a replication-terminator protein complexed with DNA.

Chain

Resolution

2.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	S88 K89 T129 F140 L153 Y156 A173 N174 K175 H176 I177 I178 K179 N180 K229 R241 Q250 H287 R288 Y289 K290 P291	S84 K85 T125 F136 L149 Y152 A169 N170 K171 H172 I173 I174 K175 N176 K225 R237 Q246 H283 R284 Y285 K286 P287
BS02	dna	A	H50 K89 A91 R93 R157 T158 S193 R198 V200 W208 R232 V234 Q237 K290 R302	H46 K85 A87 R89 R153 T154 S189 R194 V196 W204 R228 V230 Q233 K286 R298

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding

	Biological Process
GO:0006260	DNA replication
GO:0006274	DNA replication termination
GO:0071807	replication fork arrest involved in DNA replication termination

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:1ecr, PDBe:1ecr, PDBj:1ecr
PDBsum	1ecr
PubMed	8857533
UniProt	P16525\|TUS_ECOLI DNA replication terminus site-binding protein (Gene Name=tus)

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